Indian Journal of Plastic Surgery
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Year : 1987  |  Volume : 20  |  Issue : 1  |  Page : 13--17

Role of aprotinin in moderate and severe burns.


G.S.V.M. Medical college, Kanpur

Correspondence Address:
P Bhatnagar
G.S.V.M. Medical college, Kanpur

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Source of Support: None, Conflict of Interest: None


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The role of Aprotinin (Antagosan) in moderate and severe thermal burns has been studied. Patients were randomised in two groups; both receiveng same treatement with the exception that patients in trial group received Aprotinin in addition. 2000,000 K.I.U. (Kallikrein inhibition units) Aprotinin was given I.V. stat, followed six hourly,for three days. Mortality was 27.08 percent in trial group and 47.92 percent in control group (p<0.05). Aprotinin is believed to be helpful in reducing mortality in burns.






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